Can Creatine Make You Angry? Getting to the Bottom of Creatine Rumors

Every fitness enthusiast and bodybuilder knows creatine. It’s a go-to supplement for those looking to gain an edge in their workouts and enhance muscle growth.

But recently, a different kind of conversation has been surrounding this popular supplement – can creatine make you angry? A growing concern is whether creatine flexes its muscles beyond the gym and into our emotional health.

A wave of gym-goers has expressed concerns about creatine fueling their workouts and anger. With anecdotes and stories painting creatine as a potential culprit for mood swings, many ask, “Can creatine make me angry?”

In a world where we are increasingly concerned about both our physical and mental well-being, it’s essential to address these claims. So, let’s dive deep into the science behind creatine and explore whether this muscle-building aid could be causing emotional upheavals.

Can Creatine Make You Angry? Addressing the Myth

Firstly, it’s essential to understand where the notion of creatine-causing anger comes from. Anecdotal reports suggest that some individuals experience mood changes, including anger, following creatine supplementation.

But the impact of creatine on depression and moods swing was also positively connected with vitamin B12, folate, age, smoking, and alcohol consumption, serum levels of homocysteine.

However, it’s critical to note that anecdotal evidence does not equate to a scientific consensus.

Science vs. Anecdote: Does Creatine Cause Anger

Most scientific studies on creatine supplementation have centered on its benefits for physical performance and cognitive function, with little direct exploration of its impact on emotional states. The few have primarily revolved around creatine’s possible effects on depression and anxiety, with mixed findings.

One study found a negative impact of creatine supplementation on mood and anxiety in people with bipolar disorder who exhibited hypomania or mania.

To our knowledge, no well-conducted research has specifically linked creatine supplementation to increased anger or aggression. Correlation should not be mistaken for causation – just because some people who take creatine also experience anger doesn’t necessarily mean the supplement is to blame.

does creatine cause anger

Creatine and Hormonal Influence

One theory suggests that creatine could indirectly impact mood by influencing hormone levels, particularly testosterone. It’s known that fluctuations in testosterone can affect mood and aggression. However, current evidence indicates that creatine supplementation does not significantly affect testosterone levels in a way that would cause mood changes or increased anger.

The Impact of Exercise and Lifestyle Factors

It’s also worth noting that other factors could complicate the relationship between creatine and anger. For instance, intense exercise can sometimes lead to frustration or irritability due to physical exhaustion. Similarly, diet, stress, sleep quality, and other lifestyle factors can significantly influence mood and emotional stability.

Take Away

As such, it’s challenging to pin down creatine as the sole or significant contributor to increased anger. Until further research provides clearer insights, it’s advisable to consider broader lifestyle factors when assessing mood changes and to consult with a health professional if you’re concerned about the effects of any supplement on your emotional well-being.

Effects of Creatine Beyond the Anger Myth

While the claims about creatine causing anger may be more anecdotal than scientific, it’s crucial to acknowledge that, like any supplement, creatine can cause side effects. Most of these are mild and temporary, but understanding them is essential for this supplement’s safe and effective use.

Digestive Discomfort: A Common Concern

One of the most commonly reported side effects of creatine is digestive discomfort. This can include nausea, stomach cramping, and diarrhea, particularly when taking high doses or not consuming enough water.

The Dehydration Myth

Another frequently mentioned concern is that creatine can cause dehydration or muscle cramping, particularly during intense exercise. However, current research suggests that this is likely a myth. Because creatine pulls water into your muscle cells, it may help with hydration during workouts.

Creatine and Kidney Health

There are also concerns about the potential impact of creatine on kidney health. While research has shown that creatine supplementation is generally safe for healthy individuals, those with pre-existing kidney conditions should consult a doctor before starting any new supplementation regimen.

Taking Creatine Responsibly

As with any supplement, creatine should be taken moderately, responsibly, and as part of a balanced diet. Remembering supplements are not a substitute for good nutrition; a well-rounded exercise regimen is also essential.

Check 8 foods high in creatine.

Always consult a health professional before starting or changing your supplement intake, and stay well-hydrated when using creatine.

Scientific Research on Creatine and Anger

When discussing the potential links between creatine and mood changes, such as anger, it’s vital to consider what the scientific literature tells us. Interestingly, direct research into this topic is relatively limited. Most studies on creatine have focused on its performance-enhancing capabilities and cognitive benefits rather than its potential emotional side effects.

Creatine and Brain Health

However, some research has examined the role of creatine in brain health, given that the brain uses a significant amount of the body’s creatine. Some studies have found that creatine supplementation can benefit cognitive functions and may play a role in mental health disorders, such as depression and bipolar disorder.

Limited Evidence on Anger and Aggression

Unfortunately, limited scientific research links creatine use to increased anger or aggression. Most claims connecting creatine to anger are anecdotal and lack rigorous scientific backing.

Does creatine make you aggressive?

Unlike making you angry, creatine doesn’t make you aggressive. All the claims about creatine aggression are indirectly related to anecdotal evidence associated with excess physical exercise, fatigue, dehydration, and overdose.

It’s essential to understand that anecdotal evidence can often lead to misconceptions due to the lack of controlled variables and potential biases.

The Need for Further Research

While the current body of research does not conclusively link creatine supplementation to increased anger, the topic merits further investigation. It’s crucial to continue researching this area to provide clear, scientifically-backed answers to the questions posed by the public. Until then, treating claims of creatine causing anger with a healthy degree of skepticism is essential.

The Role of Supplements in Emotional Health

Nutrition and emotional health are intricately linked. We all know that what we eat can influence how we feel. For example, consuming too much caffeine can make us feel jittery while lacking certain nutrients can lead to fatigue or depression. But where does creatine, a supplement often associated with physical performance, fit into the picture of emotional health?

Creatine: The Physical and Mental Bridge

Creatine is best known for its role in energy production, particularly during high-intensity exercise. Athletes and gym-goers widely use it to help increase strength, muscle mass, and exercise performance. But creatine isn’t just involved in physical processes; it also plays a vital role in brain health.

The brain uses much of the body’s total creatine to support its functions. This fact has led researchers to explore the potential cognitive benefits of creatine supplementation. Some studies suggest that creatine may have neuroprotective effects and could improve mental performance, particularly under stress or sleep deprivation conditions.

Creatine and Mood: The Connection

The idea that creatine could impact mood comes from its role in the brain. As a substance that influences energy production in brain cells, it’s plausible that changes in creatine levels could, in theory, impact brain functions, including mood regulation.

However, the specific relationship between creatine and mood, particularly negative moods like anger, is poorly understood and requires more research.


In fitness and nutrition, it’s common for myths and misconceptions to swirl around popular supplements, and creatine is no exception.

While creatine is renowned for its performance-enhancing abilities, the claim that it causes anger is mainly anecdotal, with little scientific backing. The existing research broadly supports creatine’s safety and efficacy, while any potential link to emotional disturbances like anger remains unconfirmed.

As always, using supplements responsibly and with a balanced diet and healthy lifestyle is essential. And remember, if you have any concerns about how supplements might affect your mood or overall well-being, consult a health professional to guide you through the complexities of nutrition and emotional health.

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